After an eleven-year old girl is found suffocated with her own underwear, two step-brothers, ages 15 and 19, confess to the murder. After 30 years they were declared innocent and released.

In 1995, Hank Skinner was sentenced to death for a New Year's Eve triple-homicide of his family.

DNA from Stacey Stites' body matched Rodney Reed and he is sentenced to death. A decade later, victim's former fiancé, police officer Jimmy Fennell, is imprisoned for sexual assault. New evidence casts doubt on the declared timeline of the crime. Written by CNN

A 4-year-old girl from Philadelphia is found murdered, her body placed in a TV box. Police find no suspects, and the case goes cold. Years later, they arrest a neighbor, Walter Ogrod, for the crime. When journalist Tom Lowenstein seeks to write about the death penalty, he comes across Walter's case, and finds an investigation filled with holes, and a perpetrator whose deficits make his confession suspect. After discovering a jailhouse snitch network, Lowenstein publishes a two-part article in the Philadelphia City Paper to reveal these injustices. Meanwhile, Walter Ogrod remains on death row, fighting a system determined to keep him there.

Sabrina Butler,a 17-year old African-American woman arrives at a Mississippi hospital with her baby dead on arrival.

A babysitter is found brutally murdered in Santa Ana, California, with five young children in the home left unscathed. Kenneth Clair, a local burglar is convicted of capital murder and sent to death row.

Clarence Smitty Smith, the leader of the notorious biker club The Outlaws, is accused of a quadruple homicide in Fort Lauderdale.

After a family of six is found brutally murdered in a rural Texas town, a perpetrator confesses to the crime. Police however, can't believe one man alone could murder six people, and Anthony Graves is named as an accomplice. Graves is sentenced to death, but maintains his innocence. His case is eventually taken up by a journalism professor who discovers a District Attorney engaged in misconduct who is intent on keeping a guiltless man in prison.